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(Silicone-free) COC/COP prefilled syringe barrels with zero-degree draft angle



In May 2023, Jestar successfully developed injection molding tools for our client capable of producing silicone-free COC/COP prefilled syringe barrels with a zero-degree draft angle. As a result, Jestar is among the first toolmakers worldwide to achieve this significant milestone.



At the end of August 2024, Jestar set new industry standards on a global scale once again by successfully developing a 32-cavity tool for COC/COP prefilled syringe barrels.




Why does this represent a significant milestone?

Silicone oil has long been an essential aid in syringe manufacturing, serving as a crucial lubricant to reduce friction and ensure smooth, consistent movement of the plunger. The need for silicone oil arises from the challenges posed by the properties of plastic materials. The manufacturing process typically requires a draft angle to facilitate the release of the plastic part from the mold, making it difficult to produce syringe barrels with a zero-degree draft angle from plastic.


However, through our innovative spirit, Jestar has achieved significant progress. We have developed a groundbreaking injection molding technology with a hot runner system that enables the production of syringe barrels made from COC and COP materials with a true zero-degree draft angle, while maintaining the highest quality standards. This remarkable development thus sets a new global benchmark in the industry.


The Safest Storage for Sensitive Medications

Silicone-free syringe barrels made from COC and COP materials offer a range of compelling advantages:


  • Reduced Risk of Breakage: They significantly lower the risk of breakage, minimizing potential disruptions in critical processes.

  • Low Extractables and Leachables: These barrels exhibit minimal extractables and leachables, providing an extra layer of security for sensitive substances.

  • High Clarity: Their excellent clarity allows for good visibility, a crucial feature when precise measurements and observations are required.

  • Robust Chemical Resistance: They can withstand contact with a variety of substances, making them versatile for different applications.

  • Low Adsorption: The low adsorption properties of COC and COP materials ensure minimal interaction between the material and the contents of the syringe, which is vital for maintaining sample integrity.

  • Precision and Reduced Friction: These features enhance user experience and contribute to consistent, accurate results.

  • Impressive Heat Resistance: The materials also demonstrate excellent heat resistance, expanding their utility in scenarios involving temperature variations.


Additionally, customization options allow for adjustments to specific needs and preferences, further solidifying the status of silicone-free syringe barrels made from COC and COP materials as the preferred choice for applications where maintaining sample purity and integrity is of utmost importance. This innovation represents a significant advancement in the field, offering increased reliability and performance in critical biotech, pharmaceutical, and medical processes.

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